Mate, my best advise is not to look and listen to the strategy guides, go straight into the hospital with an AK47 or similar and full health and armor, take loads of cover with the Right Bumper/R1 and shoot everyone! once youve killed everyone in the hospital, go get the coke and find the first aid kit, ready to floor the nearest car to the building and get away from the cops! After reading all the strategy guides and stuff, it took me 2 tries to complete: first is with the help of the strategy guides and the second is with the advise I have just said! Hope this helps