no its a wierd glitch in sa. the button configuration is messed up. they forgot to put lock on aim in it. in the mission with smoke where u go to... ummm.... the first guy u can buy guns from, and he teaches you how to shoot stuff, it sez "right clikc to lock on" and then u right click and it manual aims so then w/e and you shoot the bottle. then it sez "once you have locked on, scroll our center mouse button to switch through targets to lock onto" then you right click and scroll, and nothing happens. that part relaly pissed me off to see that san andreas could have been so much easier to beat. its not a controller problem. its the game.